Nimetazepam CAS: 2011-67-8 hypnotic tranquilizer

Nimetazepam ni hypnotic ikora hagati, ikomoka kuri benzodiazepine.Yashizwemo bwa mbere mu 1964 nitsinda rya Hoffmann-La Roche.Ifite hypnotic ikomeye, kurwanya guhangayika, gutuza no kunanura imitsi ya skeletale.Nimetazepam nayo ni anticonvulsant ikora neza.Igurishwa nka tableti ya miligarama 5 yitwa Erimin, izina ryirango ryakozwe kandi rigurishwa na Sumitomo, isosiyete nini yo mu Buyapani.Ubuyapani nicyo gihugu cyonyine ku isi gitanga nimetazepam.Hanze y'Ubuyapani, Erimin iraboneka henshi mu burasirazuba no mu majyepfo y'uburasirazuba bwa Aziya kandi ikoreshwa cyane nk'ubuvuzi bw'igihe gito ku bantu bafite ikibazo cyo kudasinzira bikabije bibagora gusinzira cyangwa gusinzira.Sumitomo yahagaritse gukora Erimin kuva mu Gushyingo 2015. Iracyaboneka nka rusange cyangwa Lavol.

Nimetazepam yanditswe cyane mu myaka ya za 1980 na 1990, cyane cyane mu Buyapani, Maleziya, Brunei, Filipine, Tayilande, Indoneziya, Hong Kong na Singapore.Kubera ko ihohoterwa n’ibiyobyabwenge ryiyongereye, imiti y’ibiyobyabwenge yagabanutse cyane kuva mu 2005. Ikoreshwa cyane cyane nka antikonvansant mu bana.Iracyakoreshwa kandi mubibazo bikabije kandi binaniza byo kudasinzira mugace k’abarwayi cyangwa kuvura indwara zigihe gito.Kubwiyi ntego, ibinini bisinzira benzodiazepine Esazolam na nitrazepam byakoreshejwe kenshi kuruta nitrazepam.Imiti igabanya ubukana nka trazodone na mirtazapine cyangwa Zopiclone na zolpidem niwo murongo wa mbere wo kudasinzira.

Nubwo imiti ya nimetazepam yagabanutse, gukoresha ibiyobyabwenge bikomeje kuba byinshi muri Brunei, Singapore, Maleziya na Philippines.Bikunze gukoreshwa bifatanije na methamphetamine na ecstasy, hamwe na opioide (cyane cyane heroine cyangwa morphine).Nimetazepam irabujijwe n'amategeko muri Maleziya, bigatuma ibiyobyabwenge biba ingume, ariko ibinini byinshi byagurishijwe ku isoko ryirabura ku izina rya Nimetazepam ni impimbano.Diazepam na nitrazepam biri mubikoreshwa cyane muri benzodiazepine muri kariya karere, kandi nkibyo, bikunze kuyoborwa bikagurishwa ku isoko ryirabura, akenshi nka nitrazepam.

Gukora mu buryo butemewe na Nimezepam (bigurishwa nka Erimin-5) byamamaye muri kariya karere.Ihohoterwa rya nimetazepam ryakomeje kwiyongera muri za 2010.Gufata ibinini bya Erimin-5 byakozwe mu buryo butemewe n'amategeko byahuriranye no gufatwa na methamphetamine muri Maleziya.Umubare muto wibinini 46 bitemewe na Erimin-5 byafashwe byageragejwe kumiterere yumubiri nubumara.Ibikoresho bikora, dopant, ibanze ryibanze, hamwe n irangi bigize imiti iranga ibinini.Ibisubizo byerekanaga ko Nimetazepam aribintu byakoreshwaga cyane mubinini byafashwe.Lactose yagaragaye nkumuyoboro wingenzi mubitegererezo byinshi, ikurikirwa na mannitol hanyuma dhydcium fosifate dihydrate.Umuhondo izuba rirenze wasangaga mubinini byinshi, byakoreshejwe wenyine cyangwa bifatanije nandi marangi (urugero: tartar na Lichenol 4R) kugirango utange ibinini ibara rya pach / orange.Icyatsi kibisi murugero cyarimo ibara ry'ubururu na tartar.Diazepam ni umuti urwanya guhangayika kandi ni ingirakamaro muri kimwe gusa muri 46.Nitrazepam, imiti igabanya ubukana hamwe na hypnotic hamwe nibiyobyabwenge byababyeyi ba nitrazepam, wasangaga arikintu cya kabiri, hamwe na cafeyine nicyo kintu nyamukuru cyahujwe mubinini bitatu.

Mu 2003, Singapore yafashe ibinini 94.200 Erimin-5.Laboratoire y'Ikigo gishinzwe kurwanya ibiyobyabwenge (CNB) yakoze ibizamini ku bisate maze ibisubizo byemeza ko ari nitrazepam.