Ubushinwa butanga Lidocaine CAS 137-58-6 hamwe nigiciro cyiza
Amakuru Yibanze
gushonga muri Ethanol, ether, benzene, chloroform n'amavuta, bidashonga mumazi.Bikunze gukoreshwa hydrochloride, hydrochloride ya lidocaine (C14H22N2O · HCL, [73-78-9]) ni ifu yera ya kristaline.Ingingo yo gushonga ni 127-129 and, naho gushonga kwa monohydrate ni 77-78 ℃.Kubora cyane mumazi, 0.5% y'amazi pHO4.0-5.5.Impumuro nziza, uburyohe bwa herp.
Ikoreshwa
Igicuruzwa ni amide anesthetic yaho.Ikoreshwa cyane muri anesthesia yo hejuru, anesthesia yinjira, anesthesia ya conduction na anesthesia epidural.LD50 ya hydrochloride ya lidocaine yari 290mg / kg.
Mubikorwa byubuvuzi birimo anesthesia yinjira, anesthesia epidURAL, anesthesia yibanze (harimo anesthesia ya mucosal mugihe cya thoracoscopi cyangwa kubaga inda), hamwe no guhagarika imitsi.Epinephrine irashobora kongerwamo anestheque kugirango yongere igihe cya anesteziya kandi igabanye ingaruka nkuburozi bwa lidocaine.
Lidocaine irashobora kandi gukoreshwa mu kuvura arththmias yumuyaga nyuma yindwara ya myocardial acute, harimo kwikuramo imburagihe imburagihe, tachycardia yumuyaga, arththmias iterwa nuburozi bwa digitale, kubaga umutima hamwe na catheterisiyumu yumutima, harimo no kwikuramo imburagihe, na tachycrilia.Irakoreshwa kandi mubarwayi bafite epilepticus ititabira izindi anticonvulsants ndetse no kubatera anesthesi yaho cyangwa intraspinal.Mubisanzwe ntabwo ari byiza kurwanya arititiyumu idasanzwe.
Ibisobanuro
| izina RY'IGICURUZWA | Lidocaine |
| URUBANZA | 137-58-6 |
| MF | C14H22N2O |
| MW | 234.34 |
| EINECS | 205-302-8 |
| Ingingo yo gushonga | 66-69 ° C. |
| Ingingo yo guteka | bp4 180-182 °;bp2 159-160 ° |
| ubucucike | 0.9944 (igereranya) |
| indangagaciro | 1.5110 (igereranya) |
| Fp | 9 ℃ |
| ububiko bwa temp. | Ubike kuri RT |
| gukemura | Ethanol: 4 mg / mL |
| pka | pKa 7.88 (H2O) (Hafi) |
| ifishi | ifu |
| ibara | Umweru kugeza umuhondo |
| Amazi meza | muburyo budashobora gukemuka |
| Merk | 14.5482 |
| Igihagararo: | Ihamye.Ntibishobora kubangikanya imbaraga zikomeye za okiside. |
| InChIKey | NNJVILVZKWQKPM-UHFFFAOYSA-N |
| CAS DataBase Reba | 137-58-6 (CAS DataBase Reba) |